Key materials considerations for materials used in drug delivery include biocompatibility, stability and durability and the ability of the material to control release of the active pharmaceutical ingredient (API). At ProMed, we have extensive experience with a variety of APIs including steroids, sex hormones, microbicides, antibiotics, analgesics, and other small molecule compounds.
Silicones have long been a material of choice for drug delivery given their extreme chemical inertness, range of stable mechanical properties, and ability to compound various APIs within the matrix. Ethylene vinyl acetate (EVA) is also finding use in an increasing number of drug delivery applications. Like silicone, EVA is processed at relatively low temperatures, which helps to minimize risks associated with degradation of the API. Polyurethanes and acrylate hydrogels have also been utilized in select applications. Partnerships with leading suppliers give us access to world class implantable materials and expertise to ensure the safety and performance of your product. Typical part geometries include molded caps, rings, and cylinders as well as more complicated designs.
Another option is to use a biodegradable material such as poly(lactic-co-glycolic acid) or PLGA to controllable release the drug while essentially “dissolving away” by hydrolysis to produce lactic and glycolic acid.
To learn more, contact ProMed Pharma.